
07 Juni Lucky – Appenzeller Mix with a Hemangiosarcoma
- Patient: Lucky
- Species: Dog
- Breed: Appenzeller- Border-Mix, 12 years
- Diagnosis: hemangiosarcoma on the eye
- Pretreatment: Operation
Case description
Lucky’s hemangiosarcoma was diagnosed on February 06, 2018. The surgery was performed the following day. Initially, only the sarcoma at the lid edge was removed, but the pathologist recommended complete removal of the nictitating membrane. This surgery took place one week later. The further examination showed that no metastases could be diagnosed.

Threat of metastasis and recurrence
Cutaneous hemangiosarcoma is known to form metastases as well as to reappear with insufficient excision. It is therefore important that the tumour is removed quickly and with sufficient safety margin in healthy tissue. Due to the localisation of the tumour in the eye, it was not possible to remove the hemangiosarcoma extensively. There was a relatively high probability of recurrence and follow-up treatment was recommended.
Treatment with dendritic cells
The animal owners opted for dendritic cell therapy in the form of a treatment cycle of three applications at intervals of four weeks each from March to May 2018. There were no side effects or other problems during the treatments.
Conclusion
After three treatments with dendritic cells, the Lucky is well on. To date (June 2019) no recurrence or metastasis has occurred. Therefore, no further treatment is necessary after consultation with the animal owners.

Dr. Thomas Grammel ist Tierarzt aus Osterode am Harz. Er hat die Tierklinik Dr. Grammel in zweiter Generation seit 1989. Im Jahre hat er sie an seine Schwiegertochter Marina Grammel und seinen Sohn Dr. Lukas Grammel übergeben (heute Tiergesundheitszentrum Südharz). Im Schwerpunkt betreut Dr. Thomas Grammel deutschlandweit Tiere mit unterschiedlichen Tumorerkrankungen. Dabei behandelt er die Tiere selber vor Ort in Osterode im TGZ Südharz, er berät deutschlandweit aber auch Kolleginnen und Kollegen sowie Patientenbesitzer zu immunologischen Tumorbehandlungen mit dendritischen Zellen. Wichtig ist immer die partnerschaftliche Zusammenarbeit im Sinne der Vierbeiner.